Peptidase Inhibitor 16 (PI16) Antibody
292.5€ (80 µl)
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Name
Peptidase Inhibitor 16 (PI16) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx029735
Tested Applications
ELISA, WB
Description
Putative serine protease inhibitor (By similarity).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Peptidase Inhibitor 16 (PI16) Immunogen: KLH-conjugated synthetic peptide between 301-329 amino acids from the Central region of human PI16. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 49.5 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q6UXB8 |
| Alias | CD364,PSPBP,CRISP9,MSMBBP,PI-16,Cysteine-rich secretory protein 9,PSP94-binding protein |
| Background | Antibody anti-PI16 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Peptidase Inhibitor 16 (PI16), also known as PSPBP (prostate secretory protein binding protein), is a member of the peptidase inhibitor family that plays a role in regulating protease activity in various tissues, particularly in the cardiovascular, immune, and reproductive systems. PI16 is a secreted protein expressed primarily by stromal fibroblasts, prostate cells, and cardiac tissues, among others. It has been identified as an immunomodulatory molecule and a marker for fibroblasts, especially those involved in tissue remodeling processes. By modulating protease activity, PI16 indirectly influences extracellular matrix (ECM) composition and cellular signaling, contributing to processes like fibrosis, inflammation, and cardiac function. Given its tissue-specific expression and involvement in immune responses, PI16 has been the subject of studies focused on its roles in cardiovascular diseases, cancer, and immune regulation.
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