Mouse Peptidase Inhibitor 16 (PI16) Protein

Este producto es parte de PI16 - peptidase inhibitor 16
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208€ (10 µg)

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935106861
info@markelab.com
name
Mouse Peptidase Inhibitor 16 (PI16) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx068449
tested applications
WB, SDS-PAGE

Description

Mouse Peptidase Inhibitor 16 (PI16) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Peptidase Inhibitor 16 (PI16)
Host
E. coli
Origin
Mouse
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 53.9 kDa

Concentration: Prior to lyophilization: 200 µg/ml

Sequence Fragment: Leu21-Lys468

Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-12 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
CD364,PSPBP,CRISP9,MSMBBP,PI-16,Cysteine-rich secretory protein 9,PSP94-binding protein
Background
Protein PI16
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Peptidase Inhibitor 16 (PI16), also known as PSPBP (prostate secretory protein binding protein), is a member of the peptidase inhibitor family that plays a role in regulating protease activity in various tissues, particularly in the cardiovascular, immune, and reproductive systems. PI16 is a secreted protein expressed primarily by stromal fibroblasts, prostate cells, and cardiac tissues, among others. It has been identified as an immunomodulatory molecule and a marker for fibroblasts, especially those involved in tissue remodeling processes. By modulating protease activity, PI16 indirectly influences extracellular matrix (ECM) composition and cellular signaling, contributing to processes like fibrosis, inflammation, and cardiac function. Given its tissue-specific expression and involvement in immune responses, PI16 has been the subject of studies focused on its roles in cardiovascular diseases, cancer, and immune regulation.

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