Nucleoporin 205 (NUP205) Antibody
364€ (100 µg)
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935106861
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name
Nucleoporin 205 (NUP205) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx235923
tested applications
ELISA, WB, IHC
Description
NUP205 Antibody is a Rabbit Polyclonal against NUP205.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Nucleoporin 205 (NUP205) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q92621 |
| Gene ID | 23165 |
| OMIM | 614352 |
| Alias | NPHS13,C7orf14, Nuclear pore complex protein Nup205,205 kDa nucleoporin,chromosome 7 open reading frame 14 |
| Background | Antibody anti-NUP205 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
Nucleoporin 205 (NUP205) is a key structural component of the nuclear pore complex, contributing to the formation of the nuclear pore's central channel NUP205 works with other nucleoporins to regulate the transport of large macromolecules, such as RNA and proteins, between the nucleus and the cytoplasm It plays an important role in maintaining the selectivity and efficiency of molecular exchange, essential for processes like gene expression, cell signaling, and cellular stress responses NUP205 is involved in regulating the movement of critical proteins, such as transcription factors and cell cycle regulators, that are essential for maintaining normal cellular function Dysregulation of NUP205 is linked to several diseases, including cancers, where impaired nucleocytoplasmic transport contributes to abnormal gene expression and tumor progression Additionally, NUP205’s function in maintaining the stability and structure of the nuclear pore is critical for nuclear envelope integrity during cell division
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