Nucleoporin 205 kDa (NUP205) Antibody
273€ (100 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Nucleoporin 205 kDa (NUP205) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx102042
tested applications
WB, IHC, IF/ICC
Description
Polyclonal Antibody to Nucleoporin 205 kDa (NUP205).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Nucleoporin 205 kDa (NUP205) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | NPHS13,C7orf14, Nuclear pore complex protein Nup205,205 kDa nucleoporin,chromosome 7 open reading frame 14 |
| Background | Antibody anti-NUP205 |
| Status | RUO |
Descripción
Nucleoporin 205 (NUP205) is a key structural component of the nuclear pore complex, contributing to the formation of the nuclear pore's central channel NUP205 works with other nucleoporins to regulate the transport of large macromolecules, such as RNA and proteins, between the nucleus and the cytoplasm It plays an important role in maintaining the selectivity and efficiency of molecular exchange, essential for processes like gene expression, cell signaling, and cellular stress responses NUP205 is involved in regulating the movement of critical proteins, such as transcription factors and cell cycle regulators, that are essential for maintaining normal cellular function Dysregulation of NUP205 is linked to several diseases, including cancers, where impaired nucleocytoplasmic transport contributes to abnormal gene expression and tumor progression Additionally, NUP205’s function in maintaining the stability and structure of the nuclear pore is critical for nuclear envelope integrity during cell division
Related Products
NUP205 antibody
Plays a role in the nuclear pore complex(NPC) assembly and/or maintenance. May anchor NUP62 and other nucleoporins, but not NUP153 and TPR, to the NPC.
Ver Producto
Human Nucleoporin 205 kDa (NUP205) Protein
Recombinant Nucleoporin 205 kDa (NUP205) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Ver Producto
Nucleoporin 205 kDa (NUP205) Antibody
Polyclonal Antibody to Nucleoporin 205 kDa (NUP205).
Ver Producto