Human Nucleoporin 205 kDa (NUP205) Protein

Name: Human Nucleoporin 205 kDa (NUP205) Protein
Brand: Abbexa
SKU: abx068360
Price: 234 EUR
Availability: OnlineOnly

Este producto es parte de NUP - nucleoporin

Pida mas información

935106861

info@markelab.com

Precio

234€ (10 µg)

Protein NUP205

proveedor

Abbexa

reference

abx068360

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant Nucleoporin 205 kDa (NUP205) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).

Background

Nucleoporin 205 (NUP205) is a key structural component of the nuclear pore complex, contributing to the formation of the nuclear pore's central channel NUP205 works with other nucleoporins to regulate the transport of large macromolecules, such as RNA and proteins, between the nucleus and the cytoplasm It plays an important role in maintaining the selectivity and efficiency of molecular exchange, essential for processes like gene expression, cell signaling, and cellular stress responses NUP205 is involved in regulating the movement of critical proteins, such as transcription factors and cell cycle regulators, that are essential for maintaining normal cellular function Dysregulation of NUP205 is linked to several diseases, including cancers, where impaired nucleocytoplasmic transport contributes to abnormal gene expression and tumor progression Additionally, NUP205’s function in maintaining the stability and structure of the nuclear pore is critical for nuclear envelope integrity during cell division

Características del producto

origin

Human

host

E. coli

immunogen target

Nucleoporin 205kDa (NUP205)

host

E. coli

conjugation

Unconjugated

form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.

tested applications

WB, SDS-PAGE

size 1

10 µg

size 2

50 µg

size 3

100 µg

size 4

200 µg

size 5

500 µg

observerd MW

Molecular Weight: Calculated MW: 34.2 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Asp1735-Val2000 Tag: N-terminal His tag

expression

Recombinant

purity

> 95%

buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.

storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.

or code

NUP205

dry ice

availability

Shipped within 5-7 working days.

alias

NPHS13,C7orf14, Nuclear pore complex protein Nup205,205 kDa nucleoporin,chromosome 7 open reading frame 14

uniprot id

https://www.uniprot.org/uniprotkb/Q92621

note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

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anti- NUP205 antibody

proveedor

FineTest

reference

FNab05923

Tested Applications

ELISA, WB, IHC

reactivity

human

status

RUO

clonality

polyclonal

Plays a role in the nuclear pore complex(NPC) assembly and/or maintenance. May anchor NUP62 and other nucleoporins, but ...

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