Myomesin 1 (MYOM1) Antibody

Este producto es parte de MYOM - myomesin
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52€ (10 µg)

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935106861
info@markelab.com
name
Myomesin 1 (MYOM1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx014612
tested applications
ELISA, IHC

Description

Rabbit polyclonal antibody against MYOM1 protein. Immunogen region is Internal.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Myomesin 1 (MYOM1)
Host
Rabbit
Reactivity
Human
Recommended Dilution
IHC: 1/50 - 1/100, ELISA: 1/5000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
Size 1
10 µg
Size 2
100 µg
Size 3
200 µg
Size 4
300 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA, IHC
Buffer
PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P52179
Alias
SKELEMIN,Myomesin family member 1,190 kDa titin-associated protein,190 kDa connectin-associated protein
Background
Antibody anti-MYOM1
Status
RUO
Note
Concentration: 1 mg/ml - 

Descripción

Myomesin 1 (MYOM1) is a key structural protein located within the M-band of sarcomeres, the fundamental contractile units in muscle fibers. It serves as an essential linker between the thick myosin filaments, stabilizing the sarcomeric architecture during muscle contraction and relaxation cycles. MYOM1 plays a significant role in maintaining mechanical stability and transmitting forces generated within the sarcomere. Additionally, it interacts with other M-band proteins such as myosin-binding proteins and titin, facilitating the alignment and integrity of muscle filaments. Mutations or dysregulation in MYOM1 have been associated with muscle disorders, highlighting its critical role in both skeletal and cardiac muscle function.

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