MYOM1-Specific Antibody
364€ (100 µg)
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935106861
info@markelab.com
name
MYOM1-Specific Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx235516
tested applications
ELISA, WB, IHC
Description
MYOM1-Specific Antibody is a Rabbit Polyclonal against MYOM1-Specific.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | MYOM1-Specific |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P52179 |
| Gene ID | 8736 |
| OMIM | 603508 |
| Alias | SKELEMIN,Myomesin family member 1,190 kDa titin-associated protein,190 kDa connectin-associated protein |
| Background | Antibody anti-MYOM1 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
Myomesin 1 (MYOM1) is a key structural protein located within the M-band of sarcomeres, the fundamental contractile units in muscle fibers. It serves as an essential linker between the thick myosin filaments, stabilizing the sarcomeric architecture during muscle contraction and relaxation cycles. MYOM1 plays a significant role in maintaining mechanical stability and transmitting forces generated within the sarcomere. Additionally, it interacts with other M-band proteins such as myosin-binding proteins and titin, facilitating the alignment and integrity of muscle filaments. Mutations or dysregulation in MYOM1 have been associated with muscle disorders, highlighting its critical role in both skeletal and cardiac muscle function.
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