Mouse Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) Protein (Active)
1118€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Mouse Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) Protein (Active)
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx692006
Tested Applications
SDS-PAGE
Description
Mouse DR6 Protein is a recombinant protein from Mouse produced in HEK293 Cells. A DNA sequence encoding the mouse TNFRSF21 (NP_055267.1) extracellular domain (Met 1-His 349) was fused with a polyhistidine tag at the C-terminus.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | DR6 |
| Host | HEK293 cells |
| Assay Type | Activity: Active Sequence Fragment: Met1-His349 Tag: C-terminal His tag |
| Origin | Mouse |
| Observed MW | 35 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| NCBI Accession | NP_055267.1 |
| Alias | Tumor necrosis factor receptor superfamily member 21,DR6,CD358,BM-018,Death receptor 6 |
| Background | Protein TNFRSF21 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg of the protein as determined by the LAL method. |
Background
TNF receptor superfamily member 21 (TNFRSF21), also known as death receptor 6 (DR6), is a member of the tumor necrosis factor receptor (TNFR) superfamily. Like other TNFR members, TNFRSF21 is involved in processes that modulate immune responses, cell death, and survival pathways. This receptor is particularly involved in apoptosis, immune cell regulation, and central nervous system functions. TNFRSF21/DR6 is expressed in a range of tissues but is predominantly found in lymphoid organs, nervous system cells, and tissues associated with inflammatory processes. TNFRSF21 plays a significant role in neuroinflammation and neurodegeneration, as well as in the regulation of immune responses. It is a type I transmembrane protein that acts as a receptor for ligands like tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and amyloid precursor protein (APP)-derived peptides. Due to its involvement in cell apoptosis, particularly in neural cells, TNFRSF21 has garnered interest for its potential therapeutic applications in neurodegenerative diseases such as Alzheimer’s disease. Additionally, its function in immune cell regulation places it as a candidate target in autoimmune diseases and certain cancers.
Productos relacionados
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) Antibody
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate N…
Ver producto
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) Antibody
Rabbit Polyclonal against the TNFRSF21 protein.…
Ver producto Mouse Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) Protein
Mouse Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) is a recombinant Mouse protein expressed in E. co…
Ver producto