Mouse Transmembrane Emp24 Domain-Containing Protein 5 (TMED5) ELISA Kit

Este producto es parte de TMED - Transmembrane emp24 domain-containing
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Transmembrane Emp24 Domain-Containing Protein 5 (TMED5) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx550420
tested applications
ELISA

Description

Mouse Transmembrane emp24 domain-containing protein 5 ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Transmembrane emp24 domain-containing protein 5 concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
ELISA Kits
Immunogen Target
Transmembrane Emp24 Domain-Containing Protein 5 (TMED5)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
CGI-100, p24g2, p28,p24 family protein gamma-2 ,p24gamma2
Background
Elisa kits for TMED5
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

TMED5 is a member of the p24 trafficking protein family that regulates protein transport and sorting between the ER and the Golgi apparatus. It functions as a cargo receptor by recognizing and packaging proteins into COPII-coated vesicles for export from the ER, while facilitating vesicle retrieval back to the ER through interactions with COPI machinery. TMED5 maintains ER-Golgi communication and contributes to protein quality control, ensuring proper folding and maturation of secretory and membrane proteins. It is expressed in multiple tissues and is essential for cellular homeostasis, especially in rapidly growing or secretory cells. TMED5 also plays a role in regulating growth factor signaling pathways and maintaining Golgi structure. Dysregulation of TMED5 has been linked to developmental defects and cancers due to altered trafficking dynamics and impaired protein secretion. Knockdown studies demonstrate defective vesicle transport, Golgi fragmentation, and disrupted secretory pathway balance, emphasizing its role in protein trafficking, organelle integrity, and cellular signaling.
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