Human Transmembrane Emp24 Domain-Containing Protein 5 (TMED5) ELISA Kit
715€ (96 tests)
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name
Human Transmembrane Emp24 Domain-Containing Protein 5 (TMED5) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx550419
tested applications
ELISA
Description
Human Transmembrane emp24 domain-containing protein 5 ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Transmembrane emp24 domain-containing protein 5 concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Transmembrane Emp24 Domain-Containing Protein 5 (TMED5) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-15 working days. |
| Storage | Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9Y3A6 |
| Gene ID | 50999 |
| Alias | CGI-100, p24g2, p28,p24 family protein gamma-2 ,p24gamma2 |
| Background | Elisa Kits for: TMED5 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
TMED5 is a member of the p24 trafficking protein family that regulates protein transport and sorting between the ER and the Golgi apparatus. It functions as a cargo receptor by recognizing and packaging proteins into COPII-coated vesicles for export from the ER, while facilitating vesicle retrieval back to the ER through interactions with COPI machinery. TMED5 maintains ER-Golgi communication and contributes to protein quality control, ensuring proper folding and maturation of secretory and membrane proteins. It is expressed in multiple tissues and is essential for cellular homeostasis, especially in rapidly growing or secretory cells. TMED5 also plays a role in regulating growth factor signaling pathways and maintaining Golgi structure. Dysregulation of TMED5 has been linked to developmental defects and cancers due to altered trafficking dynamics and impaired protein secretion. Knockdown studies demonstrate defective vesicle transport, Golgi fragmentation, and disrupted secretory pathway balance, emphasizing its role in protein trafficking, organelle integrity, and cellular signaling.
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