Mouse Transcription factor E2F2 (E2F2) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for E2F2
proveedor
Abbexareference
abx520206Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Transcription factor E2F2 (E2F2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Transcription factor E2F2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
E2F2 is another member of the E2F family that functions as a key transcriptional regulator of genes involved in cell cycle progression, particularly during the G1/S transition. Like E2F1, E2F2 is regulated by the retinoblastoma protein (pRB), which controls its ability to activate target genes necessary for DNA replication and mitosis. E2F2 plays a role in balancing cell proliferation and differentiation, particularly in hematopoietic and immune cells. Dysregulation of E2F2 contributes to hyperproliferation, genomic instability, and tumorigenesis, with studies showing its overexpression in cancers such as lymphoma and leukemia. Conversely, E2F2 can act as a tumor suppressor in specific contexts by inducing cell cycle arrest or apoptosis. Knockout models exhibit impaired T cell differentiation, deregulated cell growth, and altered immune homeostasis, highlighting E2F2’s role in cell cycle regulation, immune development, and cancer biology.
Características del producto
category
ELISA Kits
immunogen target
Transcription factor E2F2 (E2F2)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
E2F-2
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
E2F2
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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