Mouse Transcription factor AP-2 gamma (TFAP2C) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for TFAP2C
proveedor
Abbexareference
abx502012Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Transcription factor AP-2 gamma (TFAP2C) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Transcription factor AP-2 gamma concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
TFAP2C, another member of the AP-2 family, regulates the transcription of genes involved in embryogenesis, cell proliferation, and epithelial cell differentiation. It is critical for early embryonic development, including trophoblast differentiation, placental development, and mammary gland morphogenesis. TFAP2C acts as a key regulator of estrogen receptor (ER)-mediated signaling in breast cancer, where it promotes tumor cell growth, survival, and metastasis. TFAP2C also regulates epithelial-mesenchymal transition (EMT), contributing to cancer progression and metastatic dissemination. Its expression is elevated in breast, ovarian, and prostate cancers, where it serves as both a prognostic marker and therapeutic target. Knockout studies reveal impaired placental development, defective cell differentiation, and embryonic lethality, emphasizing TFAP2C's role in regulating cell lineage commitment, hormone signaling, and cancer progression.
Características del producto
category
ELISA Kits
immunogen target
Transcription factor AP-2 gamma (TFAP2C)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
AP2-GAMMA,ERF1,TFAP2G,hAP-2g,Activating enhancer-binding protein 2 gamma,Transcription factor ERF-1
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
TFAP2C
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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