Mouse Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) Protein
Pida mas información
935106861
info@markelab.com
Precio
1312.5€ (200 µg)
Protein ACVRL1
proveedor
Abbexareference
abx692709Tested Applications
SDS-PAGEreactivity
status
RUOclonality
Descripción
Mouse ALK-1 Protein is a recombinant protein from Mouse produced in HEK293 Cells. A DNA sequence encoding the mouse ALK1 (NP_033742.2) precursor (Met 1-Pro 119) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
Background
ACVRL1, also known as ALK1, is a type I receptor that primarily binds BMP9 and BMP10. It is critical for vascular development and endothelial cell function. ACVRL1 regulates angiogenesis through the SMAD1/5/8 signaling pathway, promoting endothelial proliferation and vessel stability. Mutations in ACVRL1 cause hereditary hemorrhagic telangiectasia (HHT), a genetic disorder characterized by abnormal blood vessel formation and recurrent bleeding. It is primarily expressed in vascular endothelial cells.
Características del producto
category
Proteins and Peptides
origin
Mouse
host
HEK293 cells
immunogen target
ALK-1
host
HEK293 cells
tested applications
SDS-PAGE
size 1
200 µg
expression
Recombinant
purity
> 95% (SDS-PAGE)
buffer
Lyophilized from sterile PBS, pH 7.4.
storage
Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
or code
ACVRL1
dry ice
No
availability
Shipped within 5-15 working days.
alias
Activin receptor-like kinase 1,ALK-1,SKR3
NCBI accession
NP_033742.2
note
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
Quizá le pueda interesar
anti- ACVRL1 antibody
proveedor
FineTestreference
FNab00131Tested Applications
ELISA, WB, IHC, FC, IPreactivity
humanstatus
RUOclonality
polyclonalType I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel developme...
Precio a consultar
Ver másSerine/threonine-Protein Kinase Receptor R3 (ACVRL1) Antibody
proveedor
Abbexareference
abx033693Tested Applications
ELISA, WB, IHC, FCMreactivity
Human, Mousestatus
RUOclonality
PolyclonalACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors ...
281.25€ (80 µl)
Ver másSerine/threonine-Protein Kinase Receptor R3 (ACVRL1) Antibody
proveedor
Abbexareference
abx033694Tested Applications
ELISA, WB, IHC, FCMreactivity
Humanstatus
RUOclonality
PolyclonalACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors ...
281.25€ (80 µl)
Ver más