Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) Antibody

Este producto es parte de ACVR - Activin A Receptor Type
Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) Antibody

Pida mas información

935106861

info@markelab.com

Precio

337.5€ (100 µg)

Antibody anti-ACVRL1

proveedor

Abbexa

reference

abx037356

Tested Applications

ELISA, WB, IHC

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) Antibody is a Rabbit Polyclonal against Serine/threonine-Protein Kinase Receptor R3 (ACVRL1).


Background

ACVRL1, also known as ALK1, is a type I receptor that primarily binds BMP9 and BMP10. It is critical for vascular development and endothelial cell function. ACVRL1 regulates angiogenesis through the SMAD1/5/8 signaling pathway, promoting endothelial proliferation and vessel stability. Mutations in ACVRL1 cause hereditary hemorrhagic telangiectasia (HHT), a genetic disorder characterized by abnormal blood vessel formation and recurrent bleeding. It is primarily expressed in vascular endothelial cells.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human


immunogen target

Serine/threonine-Protein Kinase Receptor R3 (ACVRL1)


host

Rabbit


conjugation

Unconjugated


form

Lyophilized


tested applications

ELISA, WB, IHC


purification

Purified by antigen affinity column chromatography.


buffer

Prior to lyophilization: 1% BSA and 0.02% NaN3.


size 1

100 µg


storage

Store at -20 °C. Avoid repeated freeze/thaw cycles.


or code

ACVRL1


dry ice

No


availability

Shipped within 7-15 working days.


alias

Activin receptor-like kinase 1,ALK-1,SKR3


NCBI accession

NM_000020


note

This product is for research use only.


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