Mouse Pyroglutamylated RFamide peptide receptor (QRFPR) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for QRFPR
proveedor
Abbexareference
abx390366Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Pyroglutamylated RFamide peptide receptor (QRFPR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse QRFPR concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
QRFPR is a G protein-coupled receptor (GPCR) activated by pyroglutamylated RFamide peptides, a family of neuropeptides that play a role in regulating physiological processes such as pain modulation, feeding behavior, and hormone secretion. QRFPR primarily couples to Gq proteins, stimulating phospholipase C (PLC) and increasing intracellular calcium, leading to downstream cellular responses. It is expressed in the central nervous system, particularly in regions involved in appetite control and reward systems, as well as in peripheral tissues involved in hormone regulation. QRFPR is involved in modulating sensory processing, specifically in nociception, by influencing pain pathways. Dysregulation of QRFPR signaling is implicated in disorders related to metabolism and pain. This receptor's unique role in mediating these processes makes it a potential target for therapeutic interventions aimed at treating pain and metabolic disorders.
Características del producto
category
ELISA Kits
immunogen target
Pyroglutamylated RFamide peptide receptor (QRFPR)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.094 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
QRFPR,AQ27,SP9155,GPR103,G protein-coupled receptor 103,peptide p518 receptor
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
QRFPR
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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