G-Protein Coupled Receptor 103 (GPR103) Antibody
52€ (10 µg)
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935106861
info@markelab.com
name
G-Protein Coupled Receptor 103 (GPR103) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx015472
tested applications
ELISA, WB, IF/ICC
Description
Rabbit polyclonal antibody against GPR103 protein. Immunogen region is Internal.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | G-Protein Coupled Receptor 103 (GPR103) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/3000, IF/ICC: 1/100 - 1/500, ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96P65 |
| Alias | QRFPR,AQ27,SP9155,GPR103,G protein-coupled receptor 103,peptide p518 receptor |
| Background | Antibody anti-QRFPR |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
QRFPR is a G protein-coupled receptor (GPCR) activated by pyroglutamylated RFamide peptides, a family of neuropeptides that play a role in regulating physiological processes such as pain modulation, feeding behavior, and hormone secretion. QRFPR primarily couples to Gq proteins, stimulating phospholipase C (PLC) and increasing intracellular calcium, leading to downstream cellular responses. It is expressed in the central nervous system, particularly in regions involved in appetite control and reward systems, as well as in peripheral tissues involved in hormone regulation. QRFPR is involved in modulating sensory processing, specifically in nociception, by influencing pain pathways. Dysregulation of QRFPR signaling is implicated in disorders related to metabolism and pain. This receptor's unique role in mediating these processes makes it a potential target for therapeutic interventions aimed at treating pain and metabolic disorders.
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