Mouse Probable G-protein coupled receptor 133 (ADGRD1) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ADGRD1
proveedor
Abbexareference
abx525808Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Probable G-protein coupled receptor 133 (ADGRD1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Probable G-protein coupled receptor 133 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ADGRD1, also known as GPR133, is a member of the adhesion G protein-coupled receptor (GPCR) family, primarily involved in regulating cell signaling and adhesion. It is characterized by a large extracellular domain with a GPCR autoproteolysis-inducing (GAIN) domain, enabling receptor cleavage into an extracellular and a transmembrane subunit. ADGRD1 is highly expressed in the brain, particularly in neural stem cells, and plays a critical role in neurogenesis, neuronal migration, and maintaining blood-brain barrier integrity. It is also found in certain immune and vascular cell populations. The receptor contributes to cyclic AMP (cAMP) signaling pathways, influencing cellular growth and differentiation. Dysregulation of ADGRD1 has been associated with glioblastoma progression and altered tumor microenvironment signaling, making it a potential target for therapeutic interventions.
Características del producto
category
ELISA Kits
immunogen target
Probable G-protein coupled receptor 133 (ADGRD1)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
ADGRD1,GPR133, PGR25,G protein-coupled receptor 133
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ADGRD1
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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