Human Probable G-protein coupled receptor 133 (ADGRD1) ELISA Kit

Este producto es parte de ADGRD - Adhesion G-protein coupled receptor D
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Probable G-protein coupled receptor 133 (ADGRD1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx525807
tested applications
ELISA

Description

Human Probable G-protein coupled receptor 133 (ADGRD1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Probable G-protein coupled receptor 133 (ADGRD1) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Probable G-protein coupled receptor 133 (ADGRD1)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q6QNK2
OMIM
613639
Alias
ADGRD1,GPR133, PGR25,G protein-coupled receptor 133
Background
Elisa kits for ADGRD1
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ADGRD1, also known as GPR133, is a member of the adhesion G protein-coupled receptor (GPCR) family, primarily involved in regulating cell signaling and adhesion. It is characterized by a large extracellular domain with a GPCR autoproteolysis-inducing (GAIN) domain, enabling receptor cleavage into an extracellular and a transmembrane subunit. ADGRD1 is highly expressed in the brain, particularly in neural stem cells, and plays a critical role in neurogenesis, neuronal migration, and maintaining blood-brain barrier integrity. It is also found in certain immune and vascular cell populations. The receptor contributes to cyclic AMP (cAMP) signaling pathways, influencing cellular growth and differentiation. Dysregulation of ADGRD1 has been associated with glioblastoma progression and altered tumor microenvironment signaling, making it a potential target for therapeutic interventions.
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