Mouse Nucleoporin 188 kDa (NUP188) ELISA Kit

Este producto es parte de NUP - nucleoporin
Mouse Nucleoporin 188 kDa (NUP188) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

611€ (96 tests)

Elisa kits for NUP188

proveedor

Abbexa

reference

abx352912

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Nucleoporin 188 kDa (NUP188) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Nucleoporin 188 kDa (NUP188) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

Nucleoporin 188 (NUP188) is an essential component of the nuclear pore complex (NPC), which regulates the selective transport of molecules between the nucleus and cytoplasm NUP188 participates in the structure and function of the nuclear pore, interacting with other nucleoporins to form the central channel that facilitates the movement of RNA, proteins, and other macromolecules across the nuclear envelope NUP188 plays a significant role in ensuring the proper nuclear-cytoplasmic exchange, which is critical for maintaining cellular processes such as gene expression, signal transduction, and cell cycle regulation Additionally, NUP188 is involved in the assembly and stability of the nuclear pore complex and may influence cell division and the response to DNA damage and oxidative stress Dysregulation of NUP188 has been associated with several diseases, including cancers, where defects in nucleocytoplasmic transport lead to uncontrolled cell growth and poor prognosis NUP188’s role in maintaining nuclear structure and regulating transport underscores its importance in cellular integrity and function

Características del producto

category

ELISA Kits


immunogen target

Nucleoporin 188 kDa (NUP188)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


sensitivity

0.1 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

hNup188,KIAA0169,SANDSTEF,Nucleoporin NUP188


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

NUP188


dry ice

No


NCBI accession

NP_938046.2


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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