Mouse Nucleoporin 188 kDa (NUP188) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
611€ (96 tests)
Elisa kits for NUP188
proveedor
Abbexareference
abx352912Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Nucleoporin 188 kDa (NUP188) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Nucleoporin 188 kDa (NUP188) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Nucleoporin 188 (NUP188) is an essential component of the nuclear pore complex (NPC), which regulates the selective transport of molecules between the nucleus and cytoplasm NUP188 participates in the structure and function of the nuclear pore, interacting with other nucleoporins to form the central channel that facilitates the movement of RNA, proteins, and other macromolecules across the nuclear envelope NUP188 plays a significant role in ensuring the proper nuclear-cytoplasmic exchange, which is critical for maintaining cellular processes such as gene expression, signal transduction, and cell cycle regulation Additionally, NUP188 is involved in the assembly and stability of the nuclear pore complex and may influence cell division and the response to DNA damage and oxidative stress Dysregulation of NUP188 has been associated with several diseases, including cancers, where defects in nucleocytoplasmic transport lead to uncontrolled cell growth and poor prognosis NUP188’s role in maintaining nuclear structure and regulating transport underscores its importance in cellular integrity and function
Características del producto
category
ELISA Kits
immunogen target
Nucleoporin 188 kDa (NUP188)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
sensitivity
0.1 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
hNup188,KIAA0169,SANDSTEF,Nucleoporin NUP188
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
NUP188
dry ice
No
uniprot id
NCBI accession
NP_938046.2
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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