Human Nucleoporin 188 kDa (NUP188) Protein
247€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Nucleoporin 188 kDa (NUP188) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx068359
tested applications
WB, SDS-PAGE
Description
Recombinant Nucleoporin 188 kDa (NUP188) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Nucleoporin 188kDa (NUP188) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 53.8 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Thr540-Gly782 Tag: N-terminal His tag and GST tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q5SRE5 |
| Alias | hNup188,KIAA0169,SANDSTEF,Nucleoporin NUP188 |
| Background | Protein NUP188 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Nucleoporin 188 (NUP188) is an essential component of the nuclear pore complex (NPC), which regulates the selective transport of molecules between the nucleus and cytoplasm NUP188 participates in the structure and function of the nuclear pore, interacting with other nucleoporins to form the central channel that facilitates the movement of RNA, proteins, and other macromolecules across the nuclear envelope NUP188 plays a significant role in ensuring the proper nuclear-cytoplasmic exchange, which is critical for maintaining cellular processes such as gene expression, signal transduction, and cell cycle regulation Additionally, NUP188 is involved in the assembly and stability of the nuclear pore complex and may influence cell division and the response to DNA damage and oxidative stress Dysregulation of NUP188 has been associated with several diseases, including cancers, where defects in nucleocytoplasmic transport lead to uncontrolled cell growth and poor prognosis NUP188’s role in maintaining nuclear structure and regulating transport underscores its importance in cellular integrity and function
Related Products
Human Nucleoporin 188 kDa (NUP188) Protein
Recombinant Nucleoporin 188 kDa (NUP188) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Ver Producto
Nucleoporin 188 kDa (NUP188) Antibody
Polyclonal Antibody to Nucleoporin 188 kDa (NUP188).
Ver Producto
Mouse Nucleoporin 188 kDa (NUP188) ELISA Kit
Mouse Nucleoporin 188 kDa (NUP188) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Nucleoporin 188 kDa (NUP188) concentrations in tissue homogenates, cell lysates and other biological fluids.
Ver Producto