Name: Mouse Leucine-Rich Repeat-Containing Protein 4B (LRRC4B) ELISA Kit
Brand: Abbexa
SKU: abx531423
Price: 687.5 EUR
Availability: OnlineOnly

Background

LRRC4B, also known as netrin-G ligand 3 (NGL-3), is a transmembrane protein containing leucine-rich repeats that mediate synaptic adhesion, neuronal development, and signaling processes. It interacts with netrin-G proteins to form trans-synaptic connections that promote synapse formation, stabilization, and excitatory synaptic transmission in the central nervous system. LRRC4B is highly expressed in the brain, particularly in regions regulating learning, memory, and synaptic plasticity, where it supports the organization of neural circuits and dendritic spine maturation. Dysregulation of LRRC4B is associated with neurodevelopmental disorders, including autism spectrum disorders (ASD) and intellectual disabilities, due to impaired synaptic connectivity and function. Functional studies in knockout models demonstrate synaptic defects, abnormal neuronal morphology, and reduced synaptic transmission, emphasizing its essential role in maintaining excitatory synapse structure and function during brain development.

Características del producto

immunogen target

Leucine-Rich Repeat-Containing Protein 4B (LRRC4B)

reactivity

Mouse

test range

0.156 ng/ml - 10 ng/ml

sensitivity

< 0.07 ng/ml

assay type

Sandwich

assay data

Quantitative

detection method

Colorimetric

sample type

Tissue homogenates,Cell lysates,Other biological fluids

size 1

96 tests

alias

LRRC4B, LRIG4,Netrin-G3 ligand ,NGL-3

storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit

or code

LRRC4B

dry ice

uniprot id

https://www.uniprot.org/uniprotkb/P0C192

gene id

https://www.ncbi.nlm.nih.gov/gene/272381

note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

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Leucine-Rich Repeat-Containing Protein 4B (LRRC4B) Antibody

proveedor

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reference

abx025564

Tested Applications

ELISA, WB

reactivity

Human, Mouse

status

RUO

clonality

Polyclonal

LRRC4B Antibody is a Rabbit Polyclonal antibody against LRRC4B.

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Human Leucine-Rich Repeat-Containing Protein 4B (LRRC4B) ELISA Kit

proveedor

Abbexa

reference

abx152237

Tested Applications

ELISA

reactivity

Human

status

RUO

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687.5€ (96 tests)