Human Leucine-Rich Repeat-Containing Protein 4B (LRRC4B) ELISA Kit
715€ (96 tests)
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
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name
Human Leucine-Rich Repeat-Containing Protein 4B (LRRC4B) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx152237
tested applications
ELISA
Descripción del producto
Human Leucine-Rich Repeat-Containing Protein 4B (LRRC4B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human LRRC4B concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Especificaciones del producto
| Alias | LRRC4B, LRIG4,Netrin-G3 ligand ,NGL-3 |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Background | Elisa kits for LRRC4B |
| Category | ELISA Kits |
| Detection Method | Colorimetric |
| Dry Ice | No |
| Form | Lyophilized |
| Gene ID | 94030 |
| Immunogen Target | Leucine-Rich Repeat-Containing Protein 4B (LRRC4B) |
| Name | Human Leucine-Rich Repeat-Containing Protein 4B (LRRC4B) ELISA Kit |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
| Price | 715 |
| Provider | Abbexa |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Reference | abx152237 |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Sensitivity | < 0.16 ng/ml |
| Size 1 | 96 tests |
| Status | RUO |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Tested Applications | ELISA |
| UniProt ID | Q9NT99 |
Descripcion del producto en español
Background en español
LRRC4B, also known as netrin-G ligand 3 (NGL-3), is a transmembrane protein containing leucine-rich repeats that mediate synaptic adhesion, neuronal development, and signaling processes. It interacts with netrin-G proteins to form trans-synaptic connections that promote synapse formation, stabilization, and excitatory synaptic transmission in the central nervous system. LRRC4B is highly expressed in the brain, particularly in regions regulating learning, memory, and synaptic plasticity, where it supports the organization of neural circuits and dendritic spine maturation. Dysregulation of LRRC4B is associated with neurodevelopmental disorders, including autism spectrum disorders (ASD) and intellectual disabilities, due to impaired synaptic connectivity and function. Functional studies in knockout models demonstrate synaptic defects, abnormal neuronal morphology, and reduced synaptic transmission, emphasizing its essential role in maintaining excitatory synapse structure and function during brain development.
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