Mouse Contactin 3 (CNTN3) Protein

Este producto es parte de CNTN - contactin
Product Graph
234€ (10 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Mouse Contactin 3 (CNTN3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx066111
tested applications
WB, SDS-PAGE

Description

Recombinant Contactin 3 (CNTN3) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Contactin 3 (CNTN3)
Host
E. coli
Origin
Mouse
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 29.6 kDa

Concentration: Prior to lyophilization: 200 µg/ml

Sequence Fragment: Ser264-His493

Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q07409
Alias
PCS,PANG,BIG-1,KIAA1496,Plasmacytoma-associated neuronal glycoprotein,Brain-derived immunoglobulin superfamily protein 1,Contactin-3
Background
Protein CNTN3
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Contactin 3 (CNTN3), also known as BIG-1, is a neural adhesion molecule that belongs to the contactin family and is primarily expressed in the brain, particularly in areas involved in learning and memory, such as the hippocampus and cortex. CNTN3 mediates cell-cell adhesion and axonal interactions, contributing to synaptic formation and plasticity. It interacts with other neuronal receptors and adhesion molecules to regulate axon guidance and neuronal migration during development. CNTN3 has been implicated in neurodevelopmental disorders, including autism spectrum disorders and schizophrenia, where its dysregulation disrupts synaptic connectivity and neural circuit function. Its expression is developmentally regulated, with high levels observed during embryonic and early postnatal stages. Structurally, CNTN3 features immunoglobulin and fibronectin type III domains, facilitating homophilic and heterophilic interactions that are essential for its role in neural development. Emerging research suggests that CNTN3 may also have a role in neurodegenerative diseases and brain plasticity, though its exact mechanisms remain under investigation.

Related Products

abx066111

Mouse Contactin 3 (CNTN3) Protein

Recombinant Contactin 3 (CNTN3) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).

Ver Producto
abx100906

Contactin 3 (CNTN3) Antibody

Polyclonal Antibody to Contactin 3 (CNTN3).

Ver Producto
abx132762

Contactin 3 (CNTN3) Antibody

Contactin 3 (CNTN3) Antibody is a Rabbit Polyclonal antibody for the detection of Contactin 3 (CNTN3).

Ver Producto