Mouse Contactin 3 (CNTN3) ELISA Kit
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935106861
info@markelab.com
Precio
587.5€ (96 tests)
Elisa Kits CNTN3
proveedor
Abbexareference
abx352632Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Contactin 3 (CNTN3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Contactin 3 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Contactin 3 (CNTN3), also known as BIG-1, is a neural adhesion molecule that belongs to the contactin family and is primarily expressed in the brain, particularly in areas involved in learning and memory, such as the hippocampus and cortex. CNTN3 mediates cell-cell adhesion and axonal interactions, contributing to synaptic formation and plasticity. It interacts with other neuronal receptors and adhesion molecules to regulate axon guidance and neuronal migration during development. CNTN3 has been implicated in neurodevelopmental disorders, including autism spectrum disorders and schizophrenia, where its dysregulation disrupts synaptic connectivity and neural circuit function. Its expression is developmentally regulated, with high levels observed during embryonic and early postnatal stages. Structurally, CNTN3 features immunoglobulin and fibronectin type III domains, facilitating homophilic and heterophilic interactions that are essential for its role in neural development. Emerging research suggests that CNTN3 may also have a role in neurodegenerative diseases and brain plasticity, though its exact mechanisms remain under investigation.
Características del producto
category
ELISA Kits
immunogen target
Contactin 3 (CNTN3)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
sensitivity
0.1 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
PCS,PANG,BIG-1,KIAA1496,Plasmacytoma-associated neuronal glycoprotein,Brain-derived immunoglobulin superfamily protein 1,Contactin-3
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
CNTN3
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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