Mouse ATP-binding cassette sub-family D member 3 (ABCD3) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse ATP-binding cassette sub-family D member 3 (ABCD3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx500448
tested applications
ELISA
Description
Mouse ATP-Binding Cassette Sub-Family D Member 3 (ABCD3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse ATP-Binding Cassette Sub-Family D Member 3 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | ATP-Binding Cassette Sub-Family D Member 3 (ABCD3) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.07 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P55096 |
| Gene ID | 19299 |
| Alias | ABC43,CBAS5,PMP70 |
| Background | Elisa kits for ABCD3 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ABCD3, also known as PMP70, is a critical peroxisomal transporter involved in the import of a broad range of substrates, including bile acid intermediates, branched-chain fatty acids, and very-long-chain fatty acids (VLCFAs). It facilitates the transport of these molecules into peroxisomes, where they undergo β-oxidation or other metabolic processes. ABCD3 is highly expressed in tissues such as the liver, kidneys, and adrenal glands, reflecting its role in maintaining lipid homeostasis and detoxification. Mutations or dysregulation of ABCD3 can result in impaired peroxisomal function, contributing to disorders such as Zellweger spectrum disorders, characterized by defects in peroxisomal metabolism. ABCD3’s role in lipid transport underscores its significance in metabolic and developmental processes.
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