ATP-Binding Cassette Sub-Family D Member 3 (ABCD3) Antibody

Product specifications

Primary Antibodies

ATP-Binding Cassette Sub-Family D Member 3 (ABCD3)

Goat

Human

P-ELISA: 1/16000. Optimal dilutions/concentrations should be determined by the end user.

Polyclonal

Unconjugated

IgG

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

200 µl

Liquid

P-ELISA, IHC, FCM

Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.

Shipped within 5-10 working days.

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

No

P28288

5825

NP_002849.1, NM_002858

170995

ABC43,CBAS5,PMP70

Antibody anti-ABCD3

RUO

Concentration: 0.5 mg/ml - 

Descripción

ABCD3, also known as PMP70, is a critical peroxisomal transporter involved in the import of a broad range of substrates, including bile acid intermediates, branched-chain fatty acids, and very-long-chain fatty acids (VLCFAs). It facilitates the transport of these molecules into peroxisomes, where they undergo β-oxidation or other metabolic processes. ABCD3 is highly expressed in tissues such as the liver, kidneys, and adrenal glands, reflecting its role in maintaining lipid homeostasis and detoxification. Mutations or dysregulation of ABCD3 can result in impaired peroxisomal function, contributing to disorders such as Zellweger spectrum disorders, characterized by defects in peroxisomal metabolism. ABCD3’s role in lipid transport underscores its significance in metabolic and developmental processes.

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