935106861
info@markelab.com
Precio
687.5€ (96 tests)
Mouse Anterior gradient protein 2 homolog (AGR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Anterior gradient protein 2 homolog concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.
AGR2 is a protein involved in the endoplasmic reticulum (ER) stress response and functions as a protein disulfide isomerase (PDI), facilitating the proper folding of secreted and membrane proteins. It is primarily expressed in secretory tissues such as the gastrointestinal tract, lungs, and prostate, where it maintains ER homeostasis by catalyzing the formation of disulfide bonds in proteins. AGR2 also plays a role in cell adhesion and migration, partly through its interaction with mucins like MUC1 and MUC2. Overexpression of AGR2 is frequently observed in cancers, including breast, pancreatic, and prostate cancers, where it contributes to tumor progression, chemoresistance, and metastasis by promoting cell survival under stress conditions
ELISA Kits
Anterior gradient protein 2 homolog (AGR2)
Mouse
0.156 ng/ml - 10 ng/ml
Quantitative
Colorimetric
Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids
96 tests
AG-2,AG2,GOB-4,HAG-2,HEL-S-116,HPC8
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
AGR2
No
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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Ver másRequired for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal...
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