Mouse Anterior Gradient Protein 2 (AGR2) Protein

Este producto es parte de AGR - Anterior gradient 2, protein disulphide isomerase family member
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234€ (5 µg)

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935106861
info@markelab.com
name
Mouse Anterior Gradient Protein 2 (AGR2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx680262
tested applications
SDS-PAGE

Description

Mouse Anterior Gradient Protein 2 (AGR2) Protein is a recombinant protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Anterior Gradient Protein 2 (AGR2)
Host
E. coli
Origin
Mouse
Conjugation
Unconjugated
Expression
Recombinant
Purity
> 90% (SDS-PAGE)
Size 1
5 µg
Size 2
20 µg
Size 3
1 mg
Form
Liquid
Tested Applications
SDS-PAGE
Availability
Shipped within 5-10 working days.
Dry Ice
No
Alias
AG-2,AG2,GOB-4,HAG-2,HEL-S-116,HPC8
Background
Protein AGR2
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

AGR2 is a protein involved in the endoplasmic reticulum (ER) stress response and functions as a protein disulfide isomerase (PDI), facilitating the proper folding of secreted and membrane proteins. It is primarily expressed in secretory tissues such as the gastrointestinal tract, lungs, and prostate, where it maintains ER homeostasis by catalyzing the formation of disulfide bonds in proteins. AGR2 also plays a role in cell adhesion and migration, partly through its interaction with mucins like MUC1 and MUC2. Overexpression of AGR2 is frequently observed in cancers, including breast, pancreatic, and prostate cancers, where it contributes to tumor progression, chemoresistance, and metastasis by promoting cell survival under stress conditions

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