Mouse Anterior Gradient Protein 2 (AGR2) Protein
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935106861
info@markelab.com
Precio
208€ (10 µg)
Protein AGR2
proveedor
Abbexareference
abx065388Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant Anterior Gradient Protein 2 (AGR2) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Background
AGR2 is a protein involved in the endoplasmic reticulum (ER) stress response and functions as a protein disulfide isomerase (PDI), facilitating the proper folding of secreted and membrane proteins. It is primarily expressed in secretory tissues such as the gastrointestinal tract, lungs, and prostate, where it maintains ER homeostasis by catalyzing the formation of disulfide bonds in proteins. AGR2 also plays a role in cell adhesion and migration, partly through its interaction with mucins like MUC1 and MUC2. Overexpression of AGR2 is frequently observed in cancers, including breast, pancreatic, and prostate cancers, where it contributes to tumor progression, chemoresistance, and metastasis by promoting cell survival under stress conditions
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
Anterior Gradient Protein 2 (AGR2)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 24.6 kDa Observed MW (SDS-PAGE): 25 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Lys21-Leu175 Tag: N-terminal His tag
expression
Recombinant
purity
> 90%
buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
AGR2
dry ice
No
availability
Shipped within 5-7 working days.
alias
AG-2,AG2,GOB-4,HAG-2,HEL-S-116,HPC8
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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human,mouse,ratstatus
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