Mouse Allograft Inflammatory Factor 1 (AIF1) Protein
247€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Mouse Allograft Inflammatory Factor 1 (AIF1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx065222
tested applications
WB, SDS-PAGE
Description
Recombinant Allograft Inflammatory Factor 1 (AIF1) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Allograft Inflammatory Factor 1 (AIF1) |
| Host | E. coli |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 12.8 kDa Observed MW: 13 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Pro35-Ser102 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O70200 |
| Gene ID | 11629 |
| Alias | AIF-1,IBA1,IRT-1,IRT1 |
| Background | Protein AIF1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
AIF1 is an inflammation-responsive protein primarily expressed in macrophages, microglia, and other immune cells. It plays a critical role in immune regulation, particularly in modulating inflammatory responses, cell migration, and phagocytosis. Structurally, AIF1 contains EF-hand calcium-binding motifs, enabling it to respond to changes in intracellular calcium levels, which are key to immune cell activation and signaling. AIF1 is upregulated during inflammatory diseases such as autoimmune disorders, transplant rejection, and atherosclerosis, where it contributes to immune cell recruitment and tissue remodeling. It is also involved in promoting macrophage activation and migration to sites of injury or infection. Dysregulated AIF1 expression is associated with chronic inflammation, cancer progression, and neuroinflammatory diseases like multiple sclerosis, making it a potential biomarker and therapeutic target for inflammatory and immune-related disorders.
Related Products
Human AIF1 (Allograft inflammatory factor 1) ELISA Kit
Ver Producto
Mouse AIF1 (Allograft inflammatory factor 1) ELISA Kit
Ver Producto