Mouse Agr2(Anterior gradient protein 2 homolog) ELISA Kit
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935106861
info@markelab.com
name
Mouse Agr2(Anterior gradient protein 2 homolog) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EM1978
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Reactivity | mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.156-10ng/ml |
| Size 1 | 96T |
| Sample Type | Serum,Plasma,Tissue homogenates,Other biological fluids |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 6 months |
| Alias | AG-2,AG2,GOB-4,HAG-2,HEL-S-116,HPC8 |
| Background | Elisa Kits AGR2 |
| Status | RUO |
AGR2 is a protein involved in the endoplasmic reticulum (ER) stress response and functions as a protein disulfide isomerase (PDI), facilitating the proper folding of secreted and membrane proteins. It is primarily expressed in secretory tissues such as the gastrointestinal tract, lungs, and prostate, where it maintains ER homeostasis by catalyzing the formation of disulfide bonds in proteins. AGR2 also plays a role in cell adhesion and migration, partly through its interaction with mucins like MUC1 and MUC2. Overexpression of AGR2 is frequently observed in cancers, including breast, pancreatic, and prostate cancers, where it contributes to tumor progression, chemoresistance, and metastasis by promoting cell survival under stress conditions
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Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells(By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth.
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