Mouse 5-hydroxytryptamine receptor 5A (HTR5A) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse 5-hydroxytryptamine receptor 5A (HTR5A) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx500217
tested applications
ELISA
Description
Mouse 5-hydroxytryptamine receptor 5A (HTR5A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse 5-hydroxytryptamine receptor 5A concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | 5-hydroxytryptamine receptor 5A (HTR5A) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P30966 |
| Gene ID | 15563 |
| Alias | HTR5A,5-HT5A,5-HT5A receptor |
| Background | Elisa kits for HTR5A |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
HTR5A is a G protein-coupled serotonin receptor predominantly found in the central nervous system, where it modulates serotonin's effects on neuronal excitability and synaptic signaling. HTR5A is expressed in regions like the hippocampus, cortex, and hypothalamus, and it is involved in regulating functions such as learning, memory consolidation, and mood stabilization. The receptor couples to G proteins, inhibiting adenylate cyclase activity and thereby reducing intracellular cAMP levels. Studies have shown that HTR5A plays a role in mood regulation, with dysregulation linked to depression, schizophrenia, and other psychiatric disorders. Additionally, HTR5A modulates circadian rhythms and sleep patterns, suggesting its involvement in sleep regulation. Genetic variations in the HTR5A gene have been associated with altered serotonergic signaling, influencing individual susceptibility to mood disorders and response to serotonergic therapies. Although HTR5A remains less characterized compared to other serotonin receptors, it continues to be a target for developing treatments for neurological diseases, sleep disturbances, and affective disorders, highlighting its importance in serotonin-mediated signaling pathways.
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