Mothers against decapentaplegic homolog 7 (SMAD7) Antibody (FITC)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Mothers against decapentaplegic homolog 7 (SMAD7) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC for the detection of Human SMAD7.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Mothers against decapentaplegic homolog 7 (SMAD7) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O15105 |
| Background | Antibody anti-SMAD7 |
| Status | RUO |
Descripción
Related Products

SMAD7 antibody
Antagonist of signaling by TGF-beta(transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta(Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator(By similarity).
Ver Producto
Mothers Against Decapentaplegic Homolog 7 (SMAD7) Antibody
SMAD7 Antibody is a Rabbit Polyclonal Antibody against SMAD7.
Ver Producto
Mothers Against Decapentaplegic Homolog 7 (SMAD7) Antibody
SMAD7 Antibody is a Rabbit Polyclonal against SMAD7.
Ver Producto