Mothers Against Decapentaplegic Homolog 7 (SMAD7) Antibody

Product Graph
312€ (60 µl)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Mothers Against Decapentaplegic Homolog 7 (SMAD7) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx126601
tested applications
IHC, IF/ICC

Description

SMAD7 Antibody is a Rabbit Polyclonal against SMAD7.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Mothers Against Decapentaplegic Homolog 7 (SMAD7)
Immunogen: A synthetic peptide corresponding to human SMAD7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Assay Type
Concentration: 1 mg/ml
Recommended Dilution
IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
60 µl
Size 2
120 µl
Size 3
200 µl
Form
Liquid
Tested Applications
IHC, IF/ICC
Buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-7 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
O15105
Gene ID
4092
NCBI Accession
NP_005895.1
Background
Antibody anti-SMAD7
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

Related Products

FNab07999

SMAD7 antibody

Antagonist of signaling by TGF-beta(transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta(Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator(By similarity).

Ver Producto
abx005608

Mothers Against Decapentaplegic Homolog 7 (SMAD7) Antibody

SMAD7 Antibody is a Rabbit Polyclonal Antibody against SMAD7.

Ver Producto
abx126601

Mothers Against Decapentaplegic Homolog 7 (SMAD7) Antibody

SMAD7 Antibody is a Rabbit Polyclonal against SMAD7.

Ver Producto