Mothers Against Decapentaplegic Homolog 7 (SMAD7) Antibody

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
SMAD7 Antibody is a Rabbit Polyclonal Antibody against SMAD7.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | Mothers Against Decapentaplegic Homolog 7 (SMAD7) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by affinity chromatography. |
Size 1 | 60 µl |
Size 2 | 120 µl |
Size 3 | 200 µl |
Form | Liquid |
Tested Applications | WB |
Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | O15105 |
Gene ID | 4092 |
NCBI Accession | NP_005895.1 |
Background | Antibody anti-SMAD7 |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
Related Products

SMAD7 antibody
Antagonist of signaling by TGF-beta(transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta(Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator(By similarity).
Ver Producto
Mothers Against Decapentaplegic Homolog 7 (SMAD7) Antibody
SMAD7 Antibody is a Rabbit Polyclonal Antibody against SMAD7.
Ver Producto
Mothers Against Decapentaplegic Homolog 7 (SMAD7) Antibody
SMAD7 Antibody is a Rabbit Polyclonal against SMAD7.
Ver Producto