MAS Related GPR Family Member X3 (MRGPRX3) Antibody
169€ (20 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
MAS Related GPR Family Member X3 (MRGPRX3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx310057
tested applications
ELISA, IF/ICC
Description
MRGPRX3 Antibody is a Rabbit Polyclonal against MRGPRX3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | MAS Related GPR Family Member X3 (MRGPRX3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96LB0 |
| Gene ID | 117195 |
| OMIM | 607229 |
| Alias | MRGPRX3,MrgA,Mrgpra,Mrga10,SNSR1,Sensory neuron-specific G protein-coupled receptor 1,GPCR,MRGX3,SNSR1,SNSR2 |
| Background | Antibody anti-MRGPRX3 |
| Status | RUO |
Descripción
MRGPRX3 is a member of the MAS-related GPR family of receptors, similar in structure and function to MRGPRX1 and MRGPRX2. It is expressed in sensory neurons and mast cells, playing a role in the mediation of allergic responses and pain. MRGPRX3 is activated by various endogenous peptides and is involved in the release of histamine and other mediators from mast cells, contributing to allergic inflammation. It is particularly involved in the sensation of itch and may also play a role in modulating pain sensitivity and neurogenic inflammation. The receptor’s activation leads to the initiation of intracellular signaling cascades that include calcium release and other pro-inflammatory responses. Dysregulation of MRGPRX3 signaling is linked to disorders involving chronic pain, itch, and hypersensitivity. As a potential therapeutic target, MRGPRX3 could be modulated for the treatment of chronic pain conditions, allergic disorders, and inflammatory diseases.
Related Products
MAS Related GPR Family Member X3 (MRGPRX3) Antibody
MRGPRX3 Antibody is a Rabbit Polyclonal against MRGPRX3.
Ver ProductoMRGPRX3 Antibody (HRP)
MRGPRX3 Antibody (HRP) is a Rabbit Polyclonal against MRGPRX3 conjugated to HRP.
Ver Producto
MRGPRX3 Antibody (FITC)
MRGPRX3 Antibody (FITC) is a Rabbit Polyclonal against MRGPRX3 conjugated to FITC.
Ver Producto