Lysophosphatidic Acid Receptor 2 (LPAR2) Antibody

Este producto es parte de LPAR - Lysophosphatidic Acid Receptor
Lysophosphatidic Acid Receptor 2 (LPAR2) Antibody

Pida mas información

935106861

info@markelab.com

Precio

187.5€ (50 µg)

Antibody anti-LPAR2

proveedor

Abbexa

reference

abx324102

Tested Applications

ELISA, WB, IF/ICC

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

LPAR2 Antibody is a Rabbit Polyclonal against LPAR2.


Background

LPAR2 is a G protein-coupled receptor for lysophosphatidic acid (LPA), expressed predominantly in epithelial tissues, the gastrointestinal tract, and immune cells. LPAR2 activation triggers signaling through Gq, Gi, and G12/13 proteins, leading to phospholipase C (PLC) activation, calcium mobilization, and Rho-mediated cytoskeletal changes. LPAR2 regulates cell proliferation, migration, and survival, playing important roles in tissue repair, immune responses, and cancer progression. In wound healing, LPAR2 promotes epithelial cell migration and proliferation, aiding tissue regeneration. In cancer, LPAR2 signaling enhances tumor cell survival, invasion, and resistance to apoptosis, particularly in ovarian and gastrointestinal cancers. LPAR2 also modulates immune responses by regulating cytokine production and immune cell migration. Dysregulation of LPAR2 is associated with inflammatory diseases and cancer metastasis. Targeting LPAR2 with selective antagonists is being explored for treating cancers and inflammatory conditions, as it contributes to pathological cell growth, migration, and survival.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human


immunogen target

Lysophosphatidic Acid Receptor 2 (LPAR2)


host

Rabbit


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, WB, IF/ICC


purification

Purified by affinity chromatography.


buffer

PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.


size 1

50 µg


size 2

100 µg


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

LPAR2


dry ice

No


availability

Shipped within 5-10 working days.


alias

LPAR2,EDG4,LPA2,EDG-4,LPA-2,Pbx4,pre-B-cell leukemia transcription factor 4,endothelial differentiation gene 4,lysophosphatidic acid G-protein-coupled receptor 4


note

This product is for research use only.


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