Interleukin 22 (IL22) Antibody (Biotin)
728€ (50 µg)
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Name
Interleukin 22 (IL22) Antibody (Biotin)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx412346
Tested Applications
ELISA, WB
Description
Interleukin 22 (IL22) Antibody (Biotin) is a Rabbit Polyclonal antibody against Interleukin 22 (IL22).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Interleukin 22 (IL22) |
| Host | Rabbit |
| Reactivity | Pig |
| Assay Type | Concentration: 1.0 mg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purification | Purified |
| Size 1 | 50 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS. Contains sodium azide. |
| Availability | Shipped within 3-7 working days. |
| Storage | Aliquot and store at 2°C to 8°C upon receipt. |
| Dry Ice | No |
| UniProt ID | F1SH68 |
| Alias | TIFa,IL-21,IL-22,ILTIF,IL-TIF,IL-D110,zcyto18,TIFIL-23,Cytokine Zcyto18,IL-10-related T-cell-derived-inducible factor IL-TIF, |
| Background | Antibody anti-IL22 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Interleukin 22 (IL22) is a cytokine that belongs to the IL-10 family of cytokines. It plays a critical role in the innate and adaptive immune systems, particularly at epithelial barriers such as the skin, lungs, intestines, and liver. IL-22 is unique in that it primarily targets non-hematopoietic cells (e.g., epithelial cells) rather than immune cells. It promotes tissue protection, regeneration, and defense against pathogens, particularly in the context of infections and inflammatory diseases. IL-22 is primarily produced by a subset of CD4+ T cells, including Th17, Th22 cells, natural killer (NK) cells, and innate lymphoid cells (ILCs). The role of IL-22 is highly context-dependent. While it contributes to maintaining epithelial integrity and promoting tissue repair, excessive or chronic IL-22 production can exacerbate inflammatory diseases, such as psoriasis, inflammatory bowel disease (IBD), and rheumatoid arthritis (RA).
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