Interleukin 22 (IL22) Antibody

Product specifications

Primary Antibodies

Interleukin 22 (IL22)

Rabbit

Human

ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.

Polyclonal

Unconjugated

IgG

Purified by Protein A/G column chromatography.

100 µg

1 mg

Lyophilized

ELISA, WB

Prior to lyophilization: 0.02% NaN3.

Shipped within 7-15 working days.

Store at -20 °C. Avoid repeated freeze/thaw cycles.

No

BC069308

TIFa,IL-21,IL-22,ILTIF,IL-TIF,IL-D110,zcyto18,TIFIL-23,Cytokine Zcyto18,IL-10-related T-cell-derived-inducible factor IL-TIF,

Antibody anti-IL22

RUO

Concentration: Lyophilized form: Not applicable.  After reconstitution: 1 mg/ml. - 

Descripción

Interleukin 22 (IL22) is a cytokine that belongs to the IL-10 family of cytokines. It plays a critical role in the innate and adaptive immune systems, particularly at epithelial barriers such as the skin, lungs, intestines, and liver. IL-22 is unique in that it primarily targets non-hematopoietic cells (e.g., epithelial cells) rather than immune cells. It promotes tissue protection, regeneration, and defense against pathogens, particularly in the context of infections and inflammatory diseases. IL-22 is primarily produced by a subset of CD4+ T cells, including Th17, Th22 cells, natural killer (NK) cells, and innate lymphoid cells (ILCs). The role of IL-22 is highly context-dependent. While it contributes to maintaining epithelial integrity and promoting tissue repair, excessive or chronic IL-22 production can exacerbate inflammatory diseases, such as psoriasis, inflammatory bowel disease (IBD), and rheumatoid arthritis (RA).

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