Interleukin 22 (IL22) Antibody
292.5€ (80 µl)
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Name
Interleukin 22 (IL22) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx027751
Tested Applications
ELISA, WB
Description
Cytokine that contributes to the inflammatory response in vivo.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Interleukin 22 (IL22) Immunogen: KLH-conjugated synthetic peptide between 44-73 amino acids from the Central region of human IL22. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 20 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9GZX6 |
| Alias | TIFa,IL-21,IL-22,ILTIF,IL-TIF,IL-D110,zcyto18,TIFIL-23,Cytokine Zcyto18,IL-10-related T-cell-derived-inducible factor IL-TIF, |
| Background | Antibody anti-IL22 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Interleukin 22 (IL22) is a cytokine that belongs to the IL-10 family of cytokines. It plays a critical role in the innate and adaptive immune systems, particularly at epithelial barriers such as the skin, lungs, intestines, and liver. IL-22 is unique in that it primarily targets non-hematopoietic cells (e.g., epithelial cells) rather than immune cells. It promotes tissue protection, regeneration, and defense against pathogens, particularly in the context of infections and inflammatory diseases. IL-22 is primarily produced by a subset of CD4+ T cells, including Th17, Th22 cells, natural killer (NK) cells, and innate lymphoid cells (ILCs). The role of IL-22 is highly context-dependent. While it contributes to maintaining epithelial integrity and promoting tissue repair, excessive or chronic IL-22 production can exacerbate inflammatory diseases, such as psoriasis, inflammatory bowel disease (IBD), and rheumatoid arthritis (RA).
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