Human Wiskott Aldrich Syndrome Protein Family, Member 2 (WASF2) Protein

Este producto es parte de WASF - WASP family member
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1872€ (1 mg)

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935106861
info@markelab.com
name
Human Wiskott Aldrich Syndrome Protein Family, Member 2 (WASF2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx655522
tested applications
WB, SDS-PAGE

Description

Human Wiskott Aldrich Syndrome Protein Family, Member 2 (WASF2) Protein is a Recombinant Human protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryProteins and Peptides
Immunogen TargetWiskott Aldrich Syndrome Protein Family, Member 2 (WASF2)
HostE. coli
OriginHuman
ConjugationUnconjugated
Observed MWConcentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Please enquire. Tag: N-terminal His tag
ExpressionRecombinant
Purity> 90%
Size 11 mg
Size 25 mg
FormLyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested ApplicationsWB, SDS-PAGE
BufferPrior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
AvailabilityShipped within 1-2 months.
StorageStore at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry IceNo
AliasIMD2,SCAR2,WASF4,WAVE2,Actin-binding protein WASF2,Verprolin homology domain-containing protein 2,Wiskott-Aldrich syndrome protein family member 2
BackgroundProtein WASF2
StatusRUO
NoteThis product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

WASP family member 2 (WASF2), also known as WAVE2, is another member of the WASP family of proteins that regulates actin dynamics and cellular movement WASF2 is part of a multi-protein complex that activates the Arp2/3 complex to promote actin filament branching, a critical process for cellular motility, migration, and invasion WASF2 is highly expressed in cells that require dynamic cytoskeletal changes, such as in immune cells, neurons, and cancer cells In immune cells, WASF2 is involved in processes like T-cell activation and phagocytosis, while in cancer cells, it regulates cell invasion and metastasis through changes in actin remodeling Dysregulation of WASF2 is associated with diseases such as immune disorders, cancer metastasis, and neurodevelopmental disorders, where aberrant actin dynamics lead to impaired immune function or abnormal cell movement

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