Human Wiskott Aldrich Syndrome Protein Family Member 2 (WASF2) ELISA Kit

Este producto es parte de WASF - WASP family member
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Wiskott Aldrich Syndrome Protein Family Member 2 (WASF2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx153496
tested applications
ELISA

Description

Human Wiskott Aldrich Syndrome Protein Family Member 2 (WASF2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human WASF2 concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Wiskott Aldrich Syndrome Protein Family, Member 2 (WASF2)

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetWiskott Aldrich Syndrome Protein Family Member 2 (WASF2)
ReactivityHuman
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich
Test Range0.312 ng/ml - 20 ng/ml
Sensitivity< 0.11 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
Size 25 × 96 tests
Size 310 × 96 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeTissue homogenates and other biological fluids.
AvailabilityShipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
AliasIMD2,SCAR2,WASF4,WAVE2,Actin-binding protein WASF2,Verprolin homology domain-containing protein 2,Wiskott-Aldrich syndrome protein family member 2
BackgroundElisa kits for WASF2
StatusRUO
NoteValidity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

WASP family member 2 (WASF2), also known as WAVE2, is another member of the WASP family of proteins that regulates actin dynamics and cellular movement WASF2 is part of a multi-protein complex that activates the Arp2/3 complex to promote actin filament branching, a critical process for cellular motility, migration, and invasion WASF2 is highly expressed in cells that require dynamic cytoskeletal changes, such as in immune cells, neurons, and cancer cells In immune cells, WASF2 is involved in processes like T-cell activation and phagocytosis, while in cancer cells, it regulates cell invasion and metastasis through changes in actin remodeling Dysregulation of WASF2 is associated with diseases such as immune disorders, cancer metastasis, and neurodevelopmental disorders, where aberrant actin dynamics lead to impaired immune function or abnormal cell movement

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