Human VIPR2 (Vasoactive intestinal polypeptide receptor 2) ELISA Kit
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Name
Human VIPR2 (Vasoactive intestinal polypeptide receptor 2) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH1767
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.156-10ng/ml |
| Sensitivity | 0.094ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | P41587 |
| Alias | VIPR2,VPAC,Helodermin-preferring VIP recepto,Pituitary adenylate cyclase-activating polypeptide type III recepto,PACAP type III recepto,PACAP-R-,PACAP-R,VIP2R |
| Background | Elisa kits for VIPR2 |
| Status | RUO |
Background
VIPR2 is a G protein-coupled receptor activated by vasoactive intestinal peptide (VIP), a neuropeptide that plays a central role in regulating smooth muscle relaxation, vasodilation, and neurotransmission. VIPR2 primarily couples to Gs proteins, activating adenylate cyclase, which increases intracellular cAMP levels and leads to the relaxation of smooth muscle cells and dilation of blood vessels. It is expressed in the smooth muscle of the gastrointestinal tract, heart, lungs, and brain. VIPR2 has significant roles in regulating gastrointestinal motility, vascular tone, and immune cell activity. Dysregulation of VIPR2 signaling is implicated in diseases such as asthma, irritable bowel syndrome (IBS), and inflammatory disorders. VIPR2 antagonists are being studied for their potential in treating these diseases, as they could help reduce excessive smooth muscle contraction and inflammation.
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