Human Vascular Endothelial Growth Factor D / FIGF (VEGFD) Protein
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935106861
info@markelab.com
Precio
754€ (50 µg)
Protein VEGFD
proveedor
Abbexareference
abx651572Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Vascular Endothelial Growth Factor D / FIGF (VEGFD) Protein is a Human protein produced in 293F cell.
Background
VEGFD is a member of the vascular endothelial growth factor family that primarily promotes lymphangiogenesis and angiogenesis by binding to VEGF receptors VEGFR-2 and VEGFR-3 on endothelial cells VEGFD plays a key role in the development of lymphatic vessels during embryogenesis and in tissue repair by stimulating endothelial cell proliferation and migration It is also involved in cancer progression where VEGFD expression enhances tumor angiogenesis, lymphatic metastasis, and the spread of cancer cells Elevated levels of VEGFD have been observed in cancers such as breast cancer, melanoma, and lung cancer where it promotes the formation of new lymphatic vessels for tumor dissemination Its role in vascular biology makes VEGFD a target for therapies designed to inhibit lymphangiogenesis and reduce tumor metastasis
Características del producto
category
Proteins and Peptides
origin
Human
host
293F cell
immunogen target
Vascular Endothelial Growth Factor D / FIGF (VEGFD)
host
293F cell
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
50 µg
size 2
100 µg
size 3
200 µg
size 4
500 µg
size 5
1 mg
observerd MW
Molecular Weight: Calculated MW: 13.8 kDa Observed MW: 21 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Phe93-Ser201 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
VEGFD
dry ice
No
availability
Shipped within 5-7 working days.
alias
FIGF,VEGF-D,c-Fos-induced growth factor
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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