Human Transcription Factor AP-2 Gamma (TFAP2C) ELISA Kit

Este producto es parte de TFAP2 - Transcription factor AP-2 alpha
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Transcription Factor AP-2 Gamma (TFAP2C) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx383714
tested applications
ELISA

Description

Human Transcription Factor AP-2 Gamma (TFAP2C) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Transcription Factor AP-2 Gamma (TFAP2C) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Transcription Factor AP-2 Gamma (TFAP2C)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.094 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-12 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q92754
Gene ID
7022
OMIM
601602
Alias
AP2-GAMMA,ERF1,TFAP2G,hAP-2g,Activating enhancer-binding protein 2 gamma,Transcription factor ERF-1
Background
Elisa kits for TFAP2C
Status
RUO
Note
Validity: The validity for this kit is 6 months.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

TFAP2C, another member of the AP-2 family, regulates the transcription of genes involved in embryogenesis, cell proliferation, and epithelial cell differentiation. It is critical for early embryonic development, including trophoblast differentiation, placental development, and mammary gland morphogenesis. TFAP2C acts as a key regulator of estrogen receptor (ER)-mediated signaling in breast cancer, where it promotes tumor cell growth, survival, and metastasis. TFAP2C also regulates epithelial-mesenchymal transition (EMT), contributing to cancer progression and metastatic dissemination. Its expression is elevated in breast, ovarian, and prostate cancers, where it serves as both a prognostic marker and therapeutic target. Knockout studies reveal impaired placental development, defective cell differentiation, and embryonic lethality, emphasizing TFAP2C's role in regulating cell lineage commitment, hormone signaling, and cancer progression.

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