Human TNFRSF21(Tumor necrosis factor receptor superfamily member 21) ELISA Kit
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Precio
Precio a consultar
Elisa Kits TNFRSF21
proveedor
FineTestreference
EH4485Tested Applications
reactivity
humanstatus
RUOclonality
Background
TNF receptor superfamily member 21 (TNFRSF21), also known as death receptor 6 (DR6), is a member of the tumor necrosis factor receptor (TNFR) superfamily. Like other TNFR members, TNFRSF21 is involved in processes that modulate immune responses, cell death, and survival pathways. This receptor is particularly involved in apoptosis, immune cell regulation, and central nervous system functions. TNFRSF21/DR6 is expressed in a range of tissues but is predominantly found in lymphoid organs, nervous system cells, and tissues associated with inflammatory processes. TNFRSF21 plays a significant role in neuroinflammation and neurodegeneration, as well as in the regulation of immune responses. It is a type I transmembrane protein that acts as a receptor for ligands like tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and amyloid precursor protein (APP)-derived peptides. Due to its involvement in cell apoptosis, particularly in neural cells, TNFRSF21 has garnered interest for its potential therapeutic applications in neurodegenerative diseases such as Alzheimer’s disease. Additionally, its function in immune cell regulation places it as a candidate target in autoimmune diseases and certain cancers.
Características del producto
category
ELISA Kits
reactivity
human
test range
15.625-1000pg/ml
assay type
Sandwich ELISA, Double Antibody
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Tissue homogenates,Other biological fluids
size 1
96T
alias
Tumor necrosis factor receptor superfamily member 21,DR6,CD358,BM-018,Death receptor 6
storage
2-8 °C for 6 months
or code
TNFRSF21
uniprot id
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