Human Pyroglutamylated RFamide peptide receptor (QRFPR) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Human Pyroglutamylated RFamide peptide receptor (QRFPR) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx385333
tested applications
ELISA
Description
Human Pyroglutamylated RFamide peptide receptor (QRFPR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human QRFPR concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Pyroglutamylated RFamide peptide receptor (QRFPR) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.313 ng/ml - 20 ng/ml |
| Sensitivity | < 0.188 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q96P65 |
| Gene ID | 84109 |
| OMIM | 606925 |
| Alias | QRFPR,AQ27,SP9155,GPR103,G protein-coupled receptor 103,peptide p518 receptor |
| Background | Elisa kits for QRFPR |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
QRFPR is a G protein-coupled receptor (GPCR) activated by pyroglutamylated RFamide peptides, a family of neuropeptides that play a role in regulating physiological processes such as pain modulation, feeding behavior, and hormone secretion. QRFPR primarily couples to Gq proteins, stimulating phospholipase C (PLC) and increasing intracellular calcium, leading to downstream cellular responses. It is expressed in the central nervous system, particularly in regions involved in appetite control and reward systems, as well as in peripheral tissues involved in hormone regulation. QRFPR is involved in modulating sensory processing, specifically in nociception, by influencing pain pathways. Dysregulation of QRFPR signaling is implicated in disorders related to metabolism and pain. This receptor's unique role in mediating these processes makes it a potential target for therapeutic interventions aimed at treating pain and metabolic disorders.
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