Human Pyroglutamylated RFamide peptide receptor (QRFPR) ELISA Kit

Este producto es parte de QRFPR - Pyroglutamylated RFamide peptide receptor
Human Pyroglutamylated RFamide peptide receptor (QRFPR) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for QRFPR

proveedor

Abbexa

reference

abx385333

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Pyroglutamylated RFamide peptide receptor (QRFPR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human QRFPR concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

QRFPR is a G protein-coupled receptor (GPCR) activated by pyroglutamylated RFamide peptides, a family of neuropeptides that play a role in regulating physiological processes such as pain modulation, feeding behavior, and hormone secretion. QRFPR primarily couples to Gq proteins, stimulating phospholipase C (PLC) and increasing intracellular calcium, leading to downstream cellular responses. It is expressed in the central nervous system, particularly in regions involved in appetite control and reward systems, as well as in peripheral tissues involved in hormone regulation. QRFPR is involved in modulating sensory processing, specifically in nociception, by influencing pain pathways. Dysregulation of QRFPR signaling is implicated in disorders related to metabolism and pain. This receptor's unique role in mediating these processes makes it a potential target for therapeutic interventions aimed at treating pain and metabolic disorders.

Características del producto

category

ELISA Kits


immunogen target

Pyroglutamylated RFamide peptide receptor (QRFPR)


reactivity

Human


test range

0.313 ng/ml - 20 ng/ml


sensitivity

< 0.188 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

QRFPR,AQ27,SP9155,GPR103,G protein-coupled receptor 103,peptide p518 receptor


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

QRFPR


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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