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Human P2Y Purinoceptor 2 (P2RY2) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits P2RY2
proveedor
Abbexareference
abx257435Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Purinergic Receptor P2Y, G Protein Coupled 2 (P2RY2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Purinergic Receptor P2Y, G Protein Coupled 2 (P2RY2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
P2RY2 is a G protein-coupled receptor activated by ATP and UTP, serving as a key regulator of cellular responses to extracellular nucleotides. It is widely expressed in epithelial cells, endothelial cells, and immune cells, where it couples to Gq proteins, activating phospholipase C (PLC), increasing intracellular calcium, and modulating cytoskeletal dynamics and ion transport. P2RY2 plays a critical role in regulating inflammation, wound healing, and fluid secretion. In the respiratory tract, P2RY2 mediates mucus secretion and airway hydration, making it a therapeutic target for cystic fibrosis and chronic obstructive pulmonary disease (COPD). In addition, P2RY2 is involved in vascular remodeling, angiogenesis, and immune cell recruitment during tissue repair and inflammation. Dysregulation of P2RY2 contributes to inflammatory diseases, cardiovascular dysfunction, and fibrosis. P2RY2 agonists and antagonists are being explored for their potential in treating respiratory disorders, wound healing, and chronic inflammatory conditions.
Características del producto
category
ELISA Kits
immunogen target
P2Y Purinoceptor 2 (P2RY2)
reactivity
Human
test range
23.438 pg/ml - 1500 pg/ml
sensitivity
< 14.1 pg/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
P2RY2,ATP receptor,P2U purinoceptor 1,P2Y ATP receptor 2,P2Y purinoceptor 2,purinergic receptor P2Y,HP2U, P2RU1, P2U, P2U1, P2UR, P2Y2
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
P2RY2
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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