Human Prostate and breast cancer overexpressed gene 1 protein (PBOV1) ELISA Kit

Este producto es parte de PBOV1 - Prostate And Breast Cancer Overexpressed 1
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Prostate and breast cancer overexpressed gene 1 protein (PBOV1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx537920
tested applications
ELISA

Description

Human Prostate and breast cancer overexpressed gene 1 protein (PBOV1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Prostate and breast cancer overexpressed gene 1 protein (PBOV1) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Prostate and breast cancer overexpressed gene 1 protein (PBOV1)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q9GZY1
Alias
UC28,UROC28,dJ171N11.2
Background
Elisa kits for PBOV1
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Prostate And Breast Cancer Overexpressed 1 (PBOV1), also known as UROC28, is a gene prominently overexpressed in prostate, breast, and bladder cancers, where it is thought to play a role in tumor progression and metastasis. While its precise molecular functions remain under investigation, PBOV1 is primarily associated with enhanced cell proliferation, migration, and invasion, contributing to the aggressive behavior of cancer cells. It is localized in the cytoplasm and has been suggested to interact with key signaling pathways involved in tumorigenesis, although its direct binding partners are not yet fully characterized. Its expression is regulated by epigenetic mechanisms, including promoter methylation, and high levels of PBOV1 have been correlated with poor clinical outcomes and shorter survival rates in cancer patients. PBOV1 serves as a potential biomarker for cancer diagnosis and prognosis, with studies indicating its utility in distinguishing malignant tissues from normal or benign counterparts. Efforts are being made to explore PBOV1 as a therapeutic target, as silencing its expression in preclinical models has shown to reduce tumor growth and invasiveness. Its cancer-specific overexpression and limited presence in normal tissues make it a promising candidate for targeted therapies and diagnostic tools in oncology.

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