Family main features
Prostate And Breast Cancer Overexpressed 1 (PBOV1), also known as UROC28, is a gene that encodes a protein frequently overexpressed in various cancers, notably prostate, breast, and bladder cancers. The PBOV1 gene is located on chromosome 6q23.3. Its expression is low or absent in most normal tissues but significantly elevated in certain cancerous tissues, suggesting its role in tumorigenesis and cancer progression. PBOV1 was initially identified through differential gene expression analysis, aimed at discovering genes with higher expression levels in cancerous tissues compared to normal tissues.
The exact structure of the PBOV1 protein remains not fully characterized due to limited structural studies. However, based on sequence analysis, it is predicted to be a small, soluble protein without transmembrane domains or significant homology to other known proteins, indicating it may have unique functional properties in cancer cells. The protein consists of:
PBOV1 does not belong to a large protein family with numerous subtypes but is rather a unique gene with its specific expression profile. It is often studied in the context of its overexpression in cancer rather than its belonging to a broader class of proteins.
The biological function of PBOV1 in normal physiology remains unclear, but its role in cancer has been more thoroughly investigated. Key functions and significances include:
PBOV1 (Prostate And Breast Cancer Overexpressed 1) is a protein predominantly expressed in certain cancers, with significant implications for tumor proliferation, invasion, and metastasis. While its exact biological function in normal tissues is not fully understood, its overexpression in cancer highlights its potential as a biomarker for prognosis and a target for therapeutic intervention. Understanding PBOV1's role in cancer can lead to better diagnostic and treatment strategies, offering hope for improved patient outcomes in cancers where PBOV1 is overexpressed.
Prostate And Breast Cancer Overexpressed 1 (PBOV1)
UC28,UROC28,dJ171N11.2
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Primary Antibodies, ELISA Kits) relacionados con PBOV1 - Prostate And Breast Cancer Overexpressed 1
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 4 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | PBOV1 | abx537920 | Human Prostate and breast cancer overexpressed gene 1 protein (PBOV1) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q9GZY1 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | PBOV1 | abx324913 | Prostate And Breast Cancer Overexpressed 1 (PBOV1) Antibody | Human | Polyclonal | Rabbit | Prostate And Breast Cancer Overexpressed 1 (PBOV1) | Unconjugated | ELISA, WB, IHC, IF/ICC | 187.5 | 50 µg | Q9GZY1 | RUO | |
Abbexa | PBOV1 | abx212096 | Prostate And Breast Cancer Overexpressed 1 (PBOV1) Antibody | Human | Polyclonal | Rabbit | Prostate And Breast Cancer Overexpressed 1 (PBOV1) | Unconjugated | ELISA, WB | 250 | 50 µl | Q9GZY1 | RUO | |
Abbexa | PBOV1 | abx213112 | Prostate And Breast Cancer Overexpressed 1 (PBOV1) Antibody | Human | Polyclonal | Rabbit | Prostate And Breast Cancer Overexpressed 1 (PBOV1) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | Q9GZY1 | RUO |
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